Characterisation and Development of Type-2 NKT Cells

Expansion of MAIT cells in the combined absence of NKT and γδ-T cells

C Xu, S Li, TS Fulford, SN Christo, LK Mackay, DH Gray, AP Uldrich, DG Pellicci, D I Godfrey, HF Koay

2023-08-01

Mucosal-associated invariant T (MAIT) cells, natural killer T (NKT) cells, and γδT cells are collectively referred to as ‘unconven..

A three-stage developmental pathway for human Vγ9Vδ2 T cells within the postnatal thymus

L Perriman, N Tavakolinia, S Jalali, S Li, PF Hickey, D Amann-Zalcenstein, WWH Ho, TM Baldwin, AT Piers, IE Konstantinov, J Anderson, EG Stanley, PV Licciardi, G Kannourakis, SH Naik, HF Koay, LK Mackay, SP Berzins, DG Pellicci

2023-07-01

Vγ9Vδ2 T cells are the largest population of γδ T cells in adults and can play important roles in providing effective immunity aga..

Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2

P Pymm, SJ Redmond, O Dolezal, F Mordant, E Lopez, JP Cooney, KC Davidson, ER Haycroft, CW Tan, R Seneviratna, SL Grimley, DFJ Purcell, SJ Kent, AK Wheatley, LF Wang, A Leis, A Glukhova, M Pellegrini, AW Chung, K Subbarao

2022-11-18

The development of therapeutics to prevent or treat COVID-19 remains an area of intense focus. Protein biologics, including monocl..

A high-dimensional cytometry atlas of peripheral blood over the human life span

S Jalali, CM Harpur, AT Piers, M Auladell, L Perriman, S Li, K An, J Anderson, SP Berzins, PV Licciardi, TM Ashhurst, IE Konstantinov, DG Pellicci

2022-11-01

Age can profoundly affect susceptibility to a broad range of human diseases. Children are more susceptible to some infectious dise..

Benzofuran sulfonates and small self-lipid antigens activate type II NKT cells via CD1d

CF Almeida, DGM Smith, TY Cheng, CM Harpur, E Batleska, CV Nguyen-Robertson, T Nguyen, T Thelemann, SJJ Reddiex, S Li, SBG Eckle, I van Rhijn, J Rossjohn, AP Uldrich, DB Moody, SJ Williams, DG Pellicci, DI Godfrey

2021-08-24

Natural killer T (NKT) cells detect lipids presented by CD1d. Most studies focus on type I NKT cells that express semi-invariant α..

CD36 family members are TCR-independent ligands for CD1 antigen-presenting molecules.

Nicholas A Gherardin, Samuel J Redmond, Hamish EG McWilliam, Catarina F Almeida, Katherine HA Gourley, Rebecca Seneviratna, Shihan Li, Robert De Rose, Fiona J Ross, Catriona V Nguyen-Robertson, Shian Su, Matthew E Ritchie, Jose A Villadangos, D Branch Moody, Daniel G Pellicci, Adam P Uldrich, Dale I Godfrey

2021-06-25

CD1c presents lipid-based antigens to CD1c-restricted T cells, which are thought to be a major component of the human T cell pool...

Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge

DG Pellicci, HF Koay, SP Berzins

2020-12-01

T cell lineages are defined by specialized functions and differential expression of surface antigens, cytokines and transcription ..

Development of mucosal-associated invariant T cells

HF Koay, DI Godfrey, DG Pellicci

2018-07-01

Mucosal-associated invariant T (MAIT) cells develop in the thymus and migrate into the periphery to become the largest antigen-spe..